America’s Never-Ending Battle Against Flesh-Eating Worms | The Atlantic
“As Knipling watched screwworms churn through their life cycle in his government laboratory, he made an observation whose importance he could intuit but not yet put to use: Female screwworms mate only once in their entire life. If a female screwworm mates with a sterile male, she will never have any offspring. So if the environment could somehow be saturated with sterile males, Knipling surmised, screwworms would very quickly mate themselves out of existence.
But Knipling did not know how to sterilize male screwworms.”